Jorge Gandarilla;Shashank Shekhar;Wilfried Braje;Noel S. Wilson;Ana-Lucia Relo;Irini Akritopoulou-Zanze;Alan F. Gasiecki;Hongyu Zhao;Hu;Albert W. Kruger;Dennie S. Welch;Stevan W. Djuric;Sean C. Turner
发明人:
Irini Akritopoulou-Zanze,Wilfried Braje,Stevan W. Djuric,Noel S. Wilson,Sean C. Turner,Albert W. Kruger,Ana-Lucia Relo,Shashank Shekhar,Dennie S. Welch,Hongyu Zhao,Jorge Gandarilla,Alan F. Gasiecki,Hu
申请号:
US12784624
公开号:
US09187483B2
申请日:
2010.05.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present application relates to aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[c]pyrrole, and octahydrocyclohepta[c]pyrrole derivatives of formula (I)wherein R1, R2, R3, R4, R5, A, Y1, Y2, and Y3 are as defined in the specification. The present application also relates to compositions comprising such compounds, processes for making such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.