SEMLER, JOHN, R.,SELOVER, KATHLEEN,ROHDE, BERMINA, L.
申请号：
EP10761958
公开号：
EP2413786A4
申请日:
2010.03.30
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
A method of determining body exit of an ingestible capsule comprising the steps of providing (40) an ingestible capsule (20) having a pressure sensor (23), having (41) a subject ingest the capsule, recording (42a) measurements from the pressure sensor as the capsule passes through at least an end portion of a gastrointestinal tract of the subject, transmitting (44) the measurements to a processor (31) outside of the gastrointestinal tract of the subject, identifying (47) an increasing pressure sequence (65) in the measurements between a selected start time (62) and a transmission end time (63), comparing (48) the sequence to a reference (66), and using the comparison to make a determination (52) regarding the capsule exiting the gastrointestinal tract of the subject. The increasing pressure sequence may be the longest increasing pressure sequence in the measurements. The reference may be a logarithmic regression of the measurements. The ingestible capsule may further comprise a temperature sensor (22) and the method may further comprising the steps of recording (42b) measurements from the temperature sensor as the capsule passes through the end portion of the gastrointestinal tract of the subject, transmitting (43) the measurements to the processor, analyzing (46) the temperature measurements for a substantial drop (68) in the temperature measurements, and using the analysis of the temperature measurements to make the determination regarding the capsule exiting the gastrointestinal tract of the subject.Linvention concerne un procédé de détermination de la sortie du corps dune gélule ingérable, qui comprend les étapes suivantes : la mise à disposition (40) dune gélule ingérable (20) contenant un détecteur de pression (23), lingestion (41) de la gélule par un sujet, lenregistrement (42a) de mesures du détecteur de pression lorsque la gélule traverse au moins une partie terminale du tractus gastro-intestinal du sujet, la transmission (44) des mesures à un processeur (3
