An apparatus for deploying hemostatic clips (702) comprises a shaft connectedto a handle and a control linkage (726) in combination with a magazine (800) containinga plurality of clips arranged in a chain (700), wherein a proximal-most one ofthe clips is coupled to the control linkage and a distal portion of the magazineis contoured to permit opening of a distal-most one of the clips during a distalstroke of the control linkage and to assist closing and locking of the distal-mostclip during a proximal stroke of the control linkage . The magazine includes anexpanded chamber (810) sized to allow opening in any rotational orientationof a clip immediately proximal to the distal-most clip to a degree sufficientto disengage the distal-most clip.
