JEJU NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;제주대학교 산학협력단
发明人:
KOH, YOUNG SANG,고영상,KANG, HEE KYOUNG,강희경,HYUN, JIN WON,현진원
申请号:
KR1020120011377
公开号:
KR1020130090223A
申请日:
2012.02.03
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
PURPOSE: A composition including the extract of carpinus tschonoskii leaves as an active ingredient is provided to effectively inhibit the production of interleukin-12 p40, interleukin-6 and TNF-α, thereby being usefully used for prevention and treatment of autoimmune disease cause by the interleukin-12 p40, interleukin-6 and TNF-α. CONSTITUTION: A composition for the prevention and treatment of autoimmune disease includes the extract of carpinus tschonoskii leaves as an active ingredient. The autoimmune disease is one selected from multiple sclerosis (MS), psoriasis, rheumatoid arthritis, Crohn's disease, ulcerative colitis, type 1 diabetes mellitus, inflammatory bowel disease or systemic lupus. A pharmaceutical composition for the prevention and treatment of the autoimmune disease includes at least one additive selected from a group consisting of a carrier, a diluting agent, a disintegrating agent, a sweetener, a coating agent, an expander, a lubricant, glydents, a flavoring agent, an antioxidant, a buffer solution, a bacteriostatic agent, a diluent, a dispersing agent, a surfactant and a binder.본 발명은 개서어나무 잎 추출물을 유효성분으로 함유하는 자가면역질환의 예방 및 치료용 조성물을 제공하고자 한다.