Barney Yoo,Thomas P. Quinn,Michelle S. Bradbury,Ulrich Wiesner,Jason Lewis,Kai Ma,Feng Chen
申请号：
US15564315
公开号：
US20180133342A1
申请日:
2016.04.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are nanoparticle immunoconjugates useful for therapeutics and/or diagnostics. The immunoconjugates have diameter (e.g., average diameter) no greater than 20 nanometers (e.g., as measured by dynamic light scattering (DLS) in aqueous solution, e.g., saline solution). In certain embodiments, the conjugates are silica-based nanoparticles with single chain antibody fragments attached thereto.
