THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFIRS;VANDERBILT UNIVERSITY
发明人:
Alvin C. POWERS,Marcela BRISSOVA,Chunhua DAI,Neil PHILLIPS,Diane SAUNDERS
申请号:
US16620747
公开号:
US20200191787A1
申请日:
2018.06.11
申请国别(地区):
US
年份:
2020
代理人:
摘要:
In spite of significant efforts to identify β-cell-specific markers for β-cell imaging and purification, progress has been limited. Herein is disclosed a novel biomarker of human pancreatic β-cells, CD39L3 (also known as ectonucleoside triphosphate diphosphohydrolase-3 (NTPDase3)). Disclosed are compositions and methods for purifying and imaging β-cell using anti-CD39L3 antibodies.