In one embodiment, the method comprises providing tissue, preparing thetissue, and treating the tissue to improveremodeling characteristics of the tissue. The tissue may be, for example,cortical bone. Treating the tissue to improve remodelingcharacteristics may comprise heating the tissue, treating the tissue with achemical, or other. Heating the tissue may be done in theabsence of oxygen and may comprise heating the tissue in a vacuum, heating thetissue in an inert atmosphere, heating the tissue ina reducing atmosphere, coating the tissue with a protective coating andheating the tissue, or other. Further embodiments comprisetreating the tissue in supercritical fluids, for example, to dry or virallyinactivate the tissue.
