nanoComposix, Inc.;Sienna Biopharmaceuticals, Inc.
发明人:
Steven J. Oldenburg,Martin Miranda,David S. Sebba,Todd J. Harris
申请号：
US15374942
公开号：
US20170087183A1
申请日:
2016.12.09
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Embodiments of the present invention relate to methods for preparing high optical density solutions of nanoparticle, such as nanoplates, silver nanoplates or silver platelet nanoparticles, and to the solutions and substrates prepared by the methods. The process can include the addition of stabilizing agents (e.g., chemical or biological agents bound or otherwise linked to the nanoparticle surface) that stabilize the nanoparticle before, during, and/or after concentration, thereby allowing for the production of a stable, high optical density solution of silver nanoplates. The process can also include increasing the concentration of silver nanoplates within the solution, and thus increasing the solution optical density.
