The California Institute for Biomedical Research;The Scripps Research Institute
发明人:
Shen, Weijun,Yang, Pengyu,Zou, Huafei,Schultz, Peter G.
申请号:
AU2014364589
公开号:
AU2014364589A1
申请日:
2014.12.17
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Methods and compositions are provided for extending the half-life of a therapeutic agent. A modified therapeutic agent (mTA) comprises a therapeutic agent, a staple, and a half-life extending molecule. The mTAs disclosed herein may be used to treat a disease or a condition in a subject in need thereof.