PROBLEM TO BE SOLVED: To provide a medical device with new functions, i.e. having excellent lubricity durability of a thin film coated on a metal substrate, sustainable for calcium ions and anticancer agents in blood while various methods have been conventionally examined in manufacturing medical guide wires or the like so as to make the coating resin layer as thin as possible, having difficulties in securing the lubricity durability itself and problems of reduction in lubricity durability due to presence of calcium ions and anticancer agents in blood.SOLUTION: A maleic anhydride copolymer compound having a specific half ester bond is immobilized on the surface of substrate to constitute a medical device.
