Substituted 1-pyrrolidinyloxy, 1-piperidinyloxy and 1-azepanyloxy compounds for treating diseases associated with oxidative stress or endothelial dysfunction
Andrew Lurie Salzman,Prakash Jagtap,Garry John Southan
申请号:
US14769078
公开号:
US09604932B2
申请日:
2014.03.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Compounds are of the class of 1-pyrrolidinyloxy,1-piperidinyloxy, and 1-azepanyloxy derivatives of formula (I):The compounds are useful in prevention, treatment or management of diseases, disorders or conditions associated with oxidative stress or endothelial dysfunction. The compounds include 2,2,5,5,-tetramethyl-3-(nitrooxymethyl)pyrrolidin-1-yl acetate.