Christopher Richard Diorio;Sripriya Venkata Ramana Rao;Syed Muzafar Shah;Eugene James Murphy;Maja Vencl-Joncic
发明人:
Sripriya Venkata Ramana Rao,Syed Muzafar Shah,Christopher Richard Diorio,Maja Vencl-Joncic,Eugene James Murphy
申请号:
US12940797
公开号:
US08524281B2
申请日:
2010.11.05
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides an oral pharmaceutical formulation comprising coated spheroids of a kinase inhibitor such as neratinib, which formulation is designed to reduce or eliminate side effects associated with existing oral formulations of kinase inhibitors.