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3-AZIDO PURINE NUCLEOTIDE PRODRUGS FOR TREATMENT OF VIRAL INFECTIONS
专利权人:
Raymond F. Schinazi; Ph.D.
发明人:
Raymond F. Schinazi, Ph.D.,John W. Mellors,Nicolas Paul Sluis-Cremer,Steven J. Coats, Ph.D.,Richard Anthony Whitaker,Brian David Herman,Jong Hyun Cho,Longhu Zhou,Hongwang Zhang
申请号:
US13132920
公开号:
US20120135951A1
申请日:
2009.12.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to compounds, compositions and methods for treating or preventing viral infections, in particular, HIV, and HBV, in human patients or other animal hosts. The compounds are 3′-azido-2′,3′-dideoxy purine monophosphates, and pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof. In particular, the compounds show potent antiviral activity against HIV-1 and HBV.
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