PATTERSON, LORI JEAN,STANGELAND, ERIC L,ZIPFEL, SHEILA,LONG, DANIEL D
申请号：
NZ59254309
公开号：
NZ592543A
申请日:
2009.11.13
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
592543 Disclosed are compounds of formula (I) where a, R1, and R3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula (I) are serotonin and norepinephrine reuptake inhibitors. Also disclosed are pharmaceutical compositions comprising the crystalline salt, processes and intermediates for preparing the crystalline salt, and methods of using the crystalline salt to treat diseases. Examples of compounds of formula (I) are: 4-[4-Fluoro-2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine 4-[2-(2,6-Difluorophenoxymethyl)phenyl]piperidine and 4-[2-(2,4,6-Trifluorophenoxymethyl)phenyl]piperidine.
