ImmunoGen, Inc;Biotest AG;DANA-FARBER CANCER INSTITUTE, INC.
发明人:
Anderson, Kenneth,Daelken, Benjamin,Bruecher, Christoph,Hideshima, Teru,Uherek, Christoph
申请号:
AU2008339913
公开号:
AU2008339913B2
申请日:
2008.12.23
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Disclosed are immunoconjugates having specificity for CD138 that diminish adhesion of CD138 expressing tumor cells to stroma cells and methods of using the same. This deminished adhesion renders the tumor cells not only susceptible to the immunconjugate, but also to other agents, in particular cytotoxic agents.