DNA encoding ehrlichia chaffeensis p156 antigen, vector, host cell, vaccine comprising the same, methods for determining whether a dog is infected with ehrlichia chaffeensis and kits for performing said procedures
"p153 and p156 antigens for the immunological diagnosis of canine and human ehrlichiosis and their uses". The present invention relates to sequences encoding two immunoreactive glycoproteins that have been cleaved from ehrlichia canis (p153 gene) and from ehrlichia chaffeensis (p156 gene). These two glycoproteins are species - specific immunoreactive orthologs that are useful as subunit vaccines and for serological and molecular diagnostics for e.g. kennels and e. chaffeensis."antígenos p153 e p156 para o diagnóstico imunológico da ehrlichiose canina e humana e usos dos mesmos". a presente invenção refere-se a seqüências que codificam duas glicoproteínas imunorreativas foram cionadas de ehrlichia canis (gene p153) e de ehrlichia chaffeensis (gene p156). estas duas glicoproteínas são ortólogos imunorreativos específicos à espécie que são úteis como vacinas em subunidades e para diagnósticos sorológicos e moleculares para e. canis e e. chaffeensis.