MUKERJI PRADIP,HUANG YUNG-SHENG,DAS TAPAS,THURMOND JENNIFER,PEREIRA SUZETTE L.
申请号：
US20030431952
公开号：
US7241619(B2)
申请日:
2003.05.08
申请国别(地区):
美国
年份:
2007
代理人:
摘要：
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., "Delta5-desaturase") and at carbon 6 (i.e., "Delta6-desaturase") and to uses thereof. In particular, Delta5-desaturase may be utilized, for example, in the conversion of dihomo-gamma-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to gamma-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
