Massachusetts Institute of Technology;The Ohio State University
发明人:
Darrell J. Irvine,Karl Dane Wittrup,Ron Weiss,Yingzhong Li,Noor Momin,Yizhou Dong
申请号：
US16739407
公开号：
US20200281994A1
申请日:
2020.01.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to synthetic oncolytic viruses comprising a lipid nanoparticle comprising one or more types of lipid and a self-amplifying replicon RNA comprising a sequence that encodes an immunomodulatory molecule.
