Krishna K. Murthi,Roland Köstler,Chase Smith,Tilman Brandstetter,Arthur F. Kluge
申请号：
US11708793
公开号：
US08450348B2
申请日:
2007.02.21
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides derivatives of squaric acid, in particular derivatives of 3,4-diamino-cyclobut-3-ene-1,2-dione and tautomers and isomers thereof, as a single stereoisomer or a mixture of stereoisomers, or as a pharmaceutically acceptable salt thereof. These compounds show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.
