Antagonistic selective binding factor of osteoprotegerin binding protein

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专利权人:

アムジエン・インコーポレーテツド

发明人:

ラジエンドラ・ブイ・デシユパンデ,アナ・ヒツツ,ウイリアム・ジエイ・ボイル,ジヨン・ケビン・サリバン

申请号：

JP2008237535

公开号：

JP5279425B2

申请日:

2008.09.17

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

Selective binding agents of osteoprotegerin binding protein (OPGbp) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to OPGbp and may be used to prevent or treat conditions relating to loss of bone mass. Nucleic acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provided.

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