According to an embodiment of the present invention, there is provided a ligation device that includes an insertion portion that has a lumen through which are passed a ligature having a first end having a contractible loop formed by a knot, and a pull thread having a folded-back portion fed through the loop an operation portion provided at a proximal end portion of the insertion portion, the operation portion including a anchoring portion to which a first end of the pull thread is anchored and a movable member movable relative to the operation portion while switching between a first state in which a second end of the pull thread is anchored to the movable member and pulled and a second state in which the ligature is pulled and the pull thread is let out simultaneously.