George Heavner;Jill Giles-Komar;Bernard Scallon;David Shealy;David M. Knight
发明人:
George Heavner,David M. Knight,Jill Giles-Komar,Bernard Scallon,David Shealy
申请号:
US13547557
公开号:
US20120282170A1
申请日:
2012.07.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS:1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.