Genetically modified blood coagulation factor X having no sugar chain and method for producing the same

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专利权人:

一般財団法人化学及血清療法研究所

发明人:

副島 見事,今村 隆幸,川村 亮一,中武 博,前屋敷 ありさ,都合 瞳

申请号：

JP2009537004

公开号：

JP5513120B2

申请日:

2008.10.08

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

A Factor X (hereinafter referred to as "FX") with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.

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中国工程科技知识中心

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http://www.ckcest.cn/home/