BHANDARI, ASHOK,PATEL, DINESH V.,ZEMEDE, GENET,MATTHEAKIS, LARRY C.,LIU, DAVID
申请号：
CA2962642
公开号：
CA2962642A1
申请日:
2015.10.01
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to peptide dimer compounds and peptide monomer compounds that potently inhibit binding of u4137 to the mucosal address in cell adhesion molecule (MAdCAM) in vivo, possess high selectivity against ct431 binding, and have high stability under gastrointestinal conditions. The present invention has been developed in response to the present state of the art, and in particular, in response to the problems and needs in the art that have not yet been fully solved by currently available integrin antagonists.
