An intestinal barrier sleeve release system includes a tubular housing having a first opening at one end and a second opening at the other end. A tubular sleeve to be released is disposed in the housing. A release body connected to the one end of the tubular sleeve is disposed at the first opening of the housing and is made of a material that can be dissolved and absorbed in human intestines. An inner sheath, a middle sheath and an outer sheath are sequentially set and move relative to each other. The inner sheath and the middle sheath are operated to move axially, the release body is disengaged from the housing, and the tubular sleeve moves out of the housing and is released at a specified position of the human intestines.