Nucleic acid comprising zwitterionic nucleotides

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专利权人:

Steffen Panzner

发明人:

Steffen Panzner

申请号：

US13003410

公开号：

US08957191B2

申请日:

2009.07.13

申请国别(地区):

US

年份:

2015

代理人:

摘要：

This invention provides pH-responsive zwitterionic nucleotides and nucleic acids comprising said nucleotides, wherein said zwitterions are constituted from one or more anionic internucleoside linkages and one or more cationic moieties and said zwitterionic nucleotides further comprise either one or more hydrophobic moieties or one or more TEEs with the general structure (I) Hydrophobic element-pH-responsive hydrophilic elements (I).

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