Piet André Maurits Maria Herdewijn,Steven Cesar Alfons De Jonghe,William John Watkins,Lee Shun Chong,Jennifer Zhang
申请号：
US12374223
公开号：
US08338435B2
申请日:
2007.06.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention provides di-, tri- and tetra-substituted pyrido(3,2-d)pyrimidine derivatives with specific substituting patterns, their pharmaceutically acceptable salts, N-oxides, solvates, pro-drugs and enantiomers, possessing unexpectedly desirable pharmaceutical properties, in particular being highly active antiviral agents. The invention also provides use of such derivatives in the treatment of viral infections and pathologic conditions associated therewith, including hepatitis C.
