The present invention relates to a composition of active ingredients in the organic solvent extract ofAndrographispaniculatastem for the use in protecting kidney functions of Diabetes patients.本發明係關於一種穿心蓮(Andrographispaniculata,AP)之有機溶劑萃取物用於保護糖尿病患者腎臟功能之用途,特徵在於該穿心蓮有機溶劑萃取物係藉由將穿心蓮之乾燥莖之乙醇粗萃取物以乙醇、正己烷、正丁醇與乙酸乙酯等有機溶劑進行萃取、濃縮及乾燥而得,且包含具有藥理活性的成分(active ingredient, 簡稱APai),主要包含230 - 400 mg/g穿心蓮內酯(Andrographolides, 簡稱A)、50 - 90 mg/g新穿心蓮內酯(Neoandrographolide, 簡稱NA)及20 - 50 mg/g去氧去氫穿心蓮內酯(14-deoxy-11,12- dehydrogen-andrographolide, 簡稱DDA)。
