ANDREW P. COMBS,EDDY W. YUE,RICHARD B. SPARKS,WENYU ZHU,JIACHENG ZHOU,QIYAN LIN,LINGKAI WENG,TAI-YUEN YUE,PINGLI LIU
申请号：
PH12014500947
公开号：
PH12014500947A1
申请日:
2014.04.29
申请国别(地区):
PH
年份:
2015
代理人:
摘要：
The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. The present invention provides, inter alia, IDO inhibitors of Formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is NH2 or CH3； R2 is C1, Br, CF3, CH3, or CN； R3 is H or F； and n is 1 or 2.
