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DÉRIVÉ DE STÉROÏDE y-LACTONE DE L'ACIDE 15,16-MÉTHYLÈNE-17-HYDROXY-19-NOR-21-CARBOXYLIQUE, SON UTILISATION ET MÉDICAMENTS CONTENANT CE DÉRIVÉ
专利权人:
BAYER INTELLECTUAL PROPERTY GMBH
发明人:
KLAR, ULRICH,KUHNKE, JOACHIM,BOHLMANN, ROLF,HUEBNER, JAN,RING, SVEN,FRENZEL, THOMAS,MENGES, FREDERIK,BORDEN, STEFFEN,MUHN, HANS, PETER,PRELLE, KATJA
申请号:
EP08868567.2
公开号:
EP2238150B1
申请日:
2008.12.23
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention relates to 15,16-methylene-17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the general chemical formula I, and R4, R6a, R6b, R7 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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