PIONEER HI-BRED INTERNATIONAL, INC.;E. I. DU PONT DE NEMOURS AND COMPANY
发明人:
XU HU,BLISS MARIE KERNODLE,MOLLIE MARY MCMAHON,ADANE KASSA,XIPING NIU,JAMES KEVIN PRESNAIL,ALBERT L LU,NINA RICHTMAN,JONATHAN WILLIAM ROBESON
申请号：
US16839691
公开号：
US20200231985A1
申请日:
2020.04.03
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
