The invention relates to 6－piperidinyl－substituted isoquinolone derivatives of the formula (I)or isoquinoline derivatives of the formula (I’)Useful for the treatment and/or prevention of diseases associated with Rho－kinase and/or Rho－kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.本發明係關於式(I)之6－六氫吡啶基－取代之異喹啉酮衍生物或式(I’)之異喹啉酮衍生物其可用於治療及/或預防伴隨Rho－激酶及/或經Rho－激酶媒介之肌凝蛋白輕鏈磷酸酶磷酸化之疾病，及包含此類化合物之組成物。
