Methods for amelioration of autoimmune disease using stem cells transduced with T cell receptors from IL-10 secreting T cells

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专利权人:

发明人:

Jack L. Stominger,Sze-Ling Ng

申请号：

US14501446

公开号：

US20150079052A1

申请日:

2014.09.30

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Methods, cells and vectors are provided for treating a subject for an autoimmune disease using stem cells transduced with genes encoding T cell receptors from IL-10 secreting regulatory T cells. The IL-10 secreting regulatory T cells are obtained from a donor of stem cells, the donor having been immunized with peptidic compositions used in the treatment of the autoimmune disease.

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中国工程科技知识中心

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http://www.ckcest.cn/home/