Compositions comprising a synergistic combination of a Polyene Fungicide and at least a lipopeptide and Methods for using such combinations to control fungal Pathogens.Claim 2: the composition of claim 1, wherein the at least one lipopeptide is selected from the group consisting of iturina type Compounds, compounds of Type surfactina, compounds of Type fengicina and fusaricidinas. Claim 7: the composition of claim 3, wherein the compound is a type iturina bacilomicina.Claim 8: the composition of claim 1, wherein the at least one lipopeptide is a fusaricidina. Claim 12: the composition of claim 1, wherein the at least one lipopeptide is an extract from a fermentation product which contains lipop u00e9ptidos or part thereof.Claim 13: the composition of claim 12, wherein the fermentation product which contains lipop u00e9ptidos comes from bacteria of the Bacillus species. Claim 16: the composition of claim 2, wherein the Natamycin is a Polyene Fungicide or a derivative thereof.Claim 17: the composition of claim 2, wherein the Polyene Fungicide Nystatin is or a derivative thereof. Claim 18: the composition of claim 2, wherein the Polyene Fungicide is amphotericin B or a derivative thereof.Claim: the composition of claim 2, wherein the Polyene Fungicide is aureofungina or a derivative thereof. The Method of claim claim 48: 28, wherein the application is in Post Harvest Food and The Fungal pathogen is a pathogen that is following the Harvest.The Method of Claim: the claim 51 28, wherein the application site is a Plant, Roots, Seeds, or the soil surrounding the plant and The Fungal pathogen is a fungal Plant pathogen. The Method of claim 53: claim 28, wherein the application is performed in a human or animal and fungal pathogen Candida.The Method of Claim: the claim 55 28, wherein the application is performed in a human or animal and fungal pathogen species of Aspergillus and Fusarium species and where the Polyene Fungicide is Natamycin.Composiciones que comprenden una com