Systems and methods are provided for evaluating the complexity of a stenosis or a section of a vessel. At least one image of the stenosis or the section of the vessel is provided. A geometrical feature value of the stenosis and/or or the section of the vessel is identified from the at least one image. At least one intensity feature value is determined based on a grey level intensity of the stenosis or the section of the vessel from the at least one image. A complexity value relating to the geometrical complexity of the stenosis or the section of the vessel is calculated as a function of the at least one geometrical feature value and the at least one intensity feature value of the stenosis or the section of the vessel.
