The present invention is directed toward compounds of Formula (I) as follows: wherein, R is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O)； R1 is where the crossing dashed line illustrates the bond formed joining R1 to the molecule of Formula (I)； R2 and R3 are independently OH or H, provided that R2 and R3 are not simultaneously OH； R4 is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O), provided that R and R4 are not simultaneously H； and R5 has the general formula: CH3&mdash；(CH2)n&mdash；(CH&boxH；CH&mdash；CH2)m&mdash；CH&boxH；CH&mdash；(CH2)k&mdash；； k is an integer from 0 to 7； m is an integer from 0 to 2； and n is an integer from 0 to 10, or a pharmaceutical salt thereof. Methods of making and using these compounds are also disclosed.
