BOSTON MEDICAL CENTER CORPORATION;TRUSTEES OF BOSTON UNIVERSITY
发明人:
Lisa GANLEY-LEAL,John H. CONNOR
申请号:
US14584524
公开号:
US20150183848A1
申请日:
2014.12.29
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The methods and compositions described herein are based, in part, on the discovery of a polypeptide of soluble CD23 (sCD23) that binds and sequesters IgE. Thus, the sCD23 peptides, polypeptides and derivatives described herein are useful for treating conditions or disorders involving increased IgE levels such as e.g., allergy, anaphylaxis, inflammation, lymphoma, and certain cancers.