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FORMULATIONS D'ANTICORPS
专利权人:
LLC;MEDIMMUNE
发明人:
DIMITROVA, MARIANA, N.,MODY, NEIL
申请号:
EP11801508
公开号:
EP2588141A4
申请日:
2011.07.01
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to formulations comprising sucrose, and methods of making such formulations, wherein the sucrose content promotes the reduction or elimination of the reversible self-association (RSA) tendency of the antibody in the formulation. The present invention also relates to formulations comprising an anti-PDGFR-alpha antibody or antibody fragment. Such antibodies can be used in various methods of treatment. The application further relates to a method of eliminating or reducing the RSA tendency of antibodies in a formulation.
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中国工程科技知识中心
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