Gregory BURSHTEIN,Ariel ROTHNER,Phillip M. SCHWARTZ,Hillel GALITZER
申请号：
US15549394
公开号：
US20180036382A1
申请日:
2016.02.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A pharmaceutical composition comprising a therapeutically active agent and SNAC (sodium 8-N-(2-hydroxybenzoyl)aminocaprylate) is provided herein. The composition is formulated for oral administration and is such that the SNAC is active in enhancing absorption of the therapeutically active agent for no more than 60 minutes, and/or such that absorption of the therapeutically active agent following oral administration of the composition is characterized by a ratio of AUC to Cmax which is 60 minutes or lower and/or by a Tmax which is 60 minutes or lower. Further disclosed herein are uses and methods utilizing the compositions described herein for treating a condition treatable by oral administration of a therapeutically active agent in a subject in need thereof.
