The purpose of the present invention provides a kind of peroral formulations in what, the rare deviation because caused by individual difference, and can accurately diagnose pyridine metabolic energy exception whether there is or not or its degree and pyrimidine metabolic speed etc.. The peroral formulations are modulated and winner by by (a) compound isotopically labelled and/or pyrimidine metabolic compound and (b) sugar and/or sugar alcohol, the powder raw material of co-grinding gained.本發明之目的在於提供一種經口製劑，其少有因個體差異所引起之偏差，而可高精度地診斷吡啶代謝能異常之有無或其程度以及嘧啶代謝速度等。該經口製劑係由將(a)同位素標記化合物及/或嘧啶代謝化合物、及(b)糖及/或糖醇，混合粉碎所得之粉末原料調製而成者。
