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LIGAND DU RECEPTEUR GPR43 COUPLE A UNE PROTEINE G ET UTILISATIONS DE CE LIGAND
专利权人:
EUROSCREEN S.A.
发明人:
申请号:
EP03701488.3
公开号:
EP1463759B8
申请日:
2003.01.06
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention is related to the G-protein coupled orphan receptor GPR43 and the identification of short chain fatty acids as natural ligands of the receptor. The invention further relates to assays for the identification of agents that modulate GPR43 ligand binding and signaling activity, as well as compositions consisting essentially of an isolated GPR43 polypeptide and an isolated short chain fatty acid. The invention also relates to diagnostic methods and kits that take advantage of the novel interaction of GPR43 with short chain fatty acids.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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