BURGER, Matthew T.,RAMURTHY, Savithri,TAFT, Benjamin R.
申请号：
TN2017000075
公开号：
TN2017000075A1
申请日:
2015.09.11
申请国别(地区):
TN
年份:
2018
代理人:
摘要：
The present invention provides a compound of Formula (1), wherein X, Y, Z, R<；sub>；1<；/sub>； and R<；sub>；2<；/sub>； are as described herein, and salts thereof and therapeutic uses of these compounds for treatment of disorders associated with RAF kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic coagent.
