PROBLEM TO BE SOLVED: To provide a preventive or ameliorating agent for overactive bladder preventing and/or ameliorating urinary disturbances including urinary urgency and urge incontinence.SOLUTION: The preventive or ameliorating agent for overactive bladder comprising a perilla extract as an active ingredient is provided, whose preventing and/or ameliorating is due to ATP release inhibition.COPYRIGHT: (C)2014,JPO&INPIT【課題】過活動膀胱、又は尿意切迫感、切迫性尿失禁等の排尿障害を予防及び/又は改善する、過活動膀胱の予防又は改善剤を提供する。【解決手段】シソ抽出物を有効成分とする、過活動膀胱の予防又は改善剤。【選択図】なし