Jonathan Alexander Terrett,Demetrios Kalaitzidis,Lawrence Klein
申请号:
US16435173
公开号:
US10729725B2
申请日:
2019.06.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Materials and methods for producing genome-edited cells engineered to express a chimeric antigen receptor (CAR) construct on the cell surface, and materials and methods for genome editing to modulate the expression, function, or activity of one or more immuno-oncology related genes in a cell, and materials and methods for treating a patient using the genome-edited engineered cells.