Hübner Johannes,Rossmann Friederike,Kropec Hübner Andrea
申请号：
US201415108398
公开号：
US10100103(B2)
申请日:
2014.11.17
申请国别(地区):
美国
年份:
2018
代理人:
Saliwanchik, Lloyd & Eisenschenk
摘要：
The present invention in the fields of immunology and infectious diseases relates to opsonic and protective antibodies that are specific for Gram-positive bacteria, particularly to carbohydrate structures exposed on the surface of the bacteria. The invention includes monoclonal and chimeric antibodies, as well as fragments, regions and derivatives thereof. This invention also relates to the epitope to which the antibodies of the invention bind as well as the sequences, fragments, and regions of the epitopes. Both the antibodies and peptides that encompass the epitope, and regions and fragments thereof, may be used for diagnostic, prophylactic and therapeutic applications.
