An expandable vertebral prosthesis for replacement of a vertebral body includes opposed end plates that are respectively adapted to abut two other vertebral bodies for fastening engagement therewith and a hollow expandable body interconnecting the end plates. The end plates each define a central opening which extends therethrough for receiving bone growth. The hollow expandable body includes one or more annular body sections having concentric inner and outer side walls, the inner side wall of which defines therewithin a central channel axially extending between the central opening defined in each of the first and second end plates. The central openings have a bone graft or bone growth stimulating material therein and the central channel permitting bone growth therethrough. The hollow expandable body is axially expandable such as to extend from a collapsed position to an expanded position whereby a space left by the excised vertebral body.
