A biometric authentication system and method are provided that are based on PPG signals acquired using non-invasive methods, such as pulse oximeter, for example. Compared to the other biometric authentication approaches, PPG signals are relatively easy to acquire, relatively difficult to duplicate, and can be adaptively updated, which are qualities that make them well suited for biometric authentication. However, PPG signals are often corrupted by motion artifacts (MAs) due to the unique measurement technique, i.e., placement of a sensor close to the skin. The system and method employ an MA removal algorithm to remove or mitigate MAs to provide a PPG-based biometric authentication solution that is robust and that can be implemented relatively easily and cost effectively.