A system for dilating a Eustachian tube (ET) of a patient includes a guide member and a dilation catheter. The guide member includes a bent distal portion that is configured to provide access to an opening in the ET. The dilation catheter is slidable relative to the guide member. The dilation catheter includes a shaft, an expandable element, and an actuator. The expandable element is disposed at the distal portion of the shaft. The actuator includes a grasping portion and an actuating member. The expandable element is configured to transition to an expanded configuration in response to actuation of the actuating member. The grasping portion and actuating member are configured to be grasped in a single hand of an operator to enable the operator to advance the dilation catheter relative to the guide member and to transition the expandable element between expanded and unexpanded configurations with the single hand.