A vial adapter is provided for interconnecting a vial having a closure and a fluid delivery device such as a safety syringe. The vial adapter comprises an adapter housing having a base, a shroud extending or projecting from the base and a cannula extending or projecting from the base for penetrating a rubber seal on the vial closure to thereby establish fluid communication between the vial and the vial adapter. The shroud may comprise a plurality of latitudinal slits or windows within each of which resides a flexion arm connected to the shroud, each flexion arm capable of engaging and/or retaining vial closures of any of a variety of different sizes. The vial adapter may comprise a conduit tip in fluid communication with the cannula to allow transfer of fluid to or from the safety syringe while also preventing inadvertent activation of a safety syringe needle retraction mechanism.本發明提供一種藥瓶轉接頭,係用於互連具有一封蓋之一藥瓶與一流體遞送裝置(諸如一安全注射器)。該藥瓶轉接頭包含一轉接頭外殼,該轉接頭外殼具有一基部、從該基部延伸或突出之一護套、及從該基部延伸或突出之一套管,該套管係用於刺穿在藥瓶封蓋上之一橡膠密封件以藉此在藥瓶與藥瓶轉接頭之間建立流體連通。該護套可包含複數個經向狹縫或窗口,在每一個經向狹縫或窗口中駐留被連接至該護套之一可撓臂,每一可撓臂可以嚙合及/或固持任何各種不同尺寸的藥瓶封蓋。該藥瓶轉接頭可包含一導管尖端,其與該套管形成流體連通以允許流體轉移至該安全注射器或從該安全注射器流出,同時亦可防止一安全注射器針縮回機構的不慎啟動。