Georg Jaeschke;Lothar Lindemann;Juergen Wichmann;Eric Vieira
发明人:
Georg Jaeschke,Lothar Lindemann,Eric Vieira,Juergen Wichmann
申请号:
US12833017
公开号:
US08334287B2
申请日:
2010.07.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to imidazole derivatives of the general formulawherein R1, R2, R3, and R4 are as defined in the specification and to pharmaceutically acceptable salts thereof. Compounds of formula I are metabotropic glutamate receptor antagonists. They can be used in the treatment or prevention of mGluR5 receptor mediated disorders.